ncRNA name | hsa-miR-24 |
ncRNA Category | miRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Homo sapiens |
Tissues/Cell_line | human umbilical vein endothelial cells (HUVECs) |
Methods | transfection, qRT-PCR, Northern blot, Western blot, luciferase reporter assay |
Expression pattern | up-regulated |
Functional description | miR-24 has been shown to regulate apoptosis and inhibit cell proliferation. In the absence of miR-23 and miR-27, there is a compensatory up-regulation of miR-24 in our in vitro and in vivo knockdown assays. The potential role of miR-24 in angiogenesis awaits future studies. |
PubMed ID | 21536891 |
Year | 2011 |
Title | Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23~27~24 clusters. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.